Riferimento farmaci
Silver sulfadiazine
Silver sulfadiazine is a medicine in the class anti bacterial. It is used for burns.
- Classe del farmaco: Anti Bacterial
- Indicato per: burns
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In breve
- Classe del farmaco
- Anti Bacterial
- Forme farmaceutiche comuni
- crema, inalatore
- Dosaggi comuni
- 1%, 10 g/1000 g, 10 mg/g
- Interazioni note
- 4 (Moderata: 4)
- Nomi commerciali
- 19
- Paesi e mercati
- 3
Per cosa si usa
Come agisce
Acts on cell membrane and cell wall
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Burn Wound Infections (2°/3°) (1% cream): Apply to thickness of 1/16 inch qDay-q12hr to burn
Gravidanza e allattamento
- Gravidanza
- Unsafe Burn cream: sulfadiazine and some silver are absorbed, more from large burns. No harm in rabbits. US label: contraindicated in women at or near term, as sulfonamides raise the risk of newborn kernicterus. Earlier in pregnancy use only if clearly justified.
- Allattamento
- Unknown Not known if it passes into milk; about 10% of the sulfadiazine is absorbed and sulfonamides reach milk. US label: decide whether to stop breastfeeding or the drug (kernicterus). e-lactancia: probably compatible. Avoid with a newborn, preterm, jaundiced or G6PD-deficient infant; never on the breast.
Effetti indesiderati segnalati
- Pain
- Erythema multiforme
- Itching
- Burning
- Necrosis of the skin
Controindicazioni
- Sulfa allergy
- Hypersensitivity
- Pregnant women at term or near term; premature infants, or in infants 2 months or younger
Chi deve prestare attenzione
- Use caution in G6PD deficiency; hemolysis may occur
- For topical use only; avoid contact with eyes
- Although silver sulfadiazine is minimally absorbed, it reacts with body fluids to release sulfadiazine, which is absorbed and may reach substantial serum concentrations
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (4)
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Domande frequenti
What is Silver sulfadiazine used for?
Silver sulfadiazine is a medicine in the class anti bacterial. It is used for Burns.
What side effects have been reported with Silver sulfadiazine?
Pain, Erythema multiforme, Itching, Burning, Necrosis of the skin.
Can Silver sulfadiazine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Burn cream: sulfadiazine and some silver are absorbed, more from large burns. No harm in rabbits. US label: contraindicated in women at or near term, as sulfonamides raise the risk of newborn kernicterus. Earlier in pregnancy use only if clearly justified. Breastfeeding: Unknown. Not known if it passes into milk; about 10% of the sulfadiazine is absorbed and sulfonamides reach milk. US label: decide whether to stop breastfeeding or the drug (kernicterus). e-lactancia: probably compatible. Avoid with a newborn, preterm, jaundiced or G6PD-deficient infant; never on the breast.
What does Silver sulfadiazine interact with?
MediHelp lists 4 known interactions for Silver sulfadiazine. Moderate: 4. The most serious include Allogeneic cultured keratinocytes and fibroblasts, Collagenase, Papain.
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