Interazioni tra farmaci
Papain + Silver sulfadiazine
Gravità: Moderata
Papain and Silver sulfadiazine: moderate interaction.
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Sintesi
Silver from silver sulfadiazine can inactivate papain, a proteolytic debriding enzyme, when both are used on the same wound. Debridement may be less effective.
Cosa significa questa interazione in parole semplici
Papain and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Silver heavy metal ions inactivate the enzyme protein.
Cosa fare
Do not use together on the same wound site. Thoroughly clean off silver sulfadiazine before applying papain.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Silver sulfadiazine
Domande frequenti
Can I take Papain with Silver sulfadiazine?
MediHelp rates the interaction as moderate. Papain and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Silver from silver sulfadiazine can inactivate papain, a proteolytic debriding enzyme, when both are used on the same wound. Debridement may be less effective.
How serious is the interaction between Papain and Silver sulfadiazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together on the same wound site. Thoroughly clean off silver sulfadiazine before applying papain.
What other medicines interact with Silver sulfadiazine?
MediHelp also lists interactions of Silver sulfadiazine with, for example, Allogeneic cultured keratinocytes and fibroblasts, Collagenase, Trypsin. The full list is on the Silver sulfadiazine page.
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