Interazioni tra farmaci
Acetylsalicylic acid + Hydrocortisone
Gravità: Moderata
Acetylsalicylic acid and Hydrocortisone: moderate interaction.
Ultimo aggiornamento
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Sintesi
Systemic corticosteroids combined with aspirin increase the risk of gastric ulceration and gastrointestinal bleeding. Corticosteroids may also lower salicylate levels, which can rise when the steroid is withdrawn.
Cosa significa questa interazione in parole semplici
Acetylsalicylic acid and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylsalicylic acid belongs to Musculoskeletal; Hydrocortisone belongs to Endocrine.
Perché avviene
Additive gastric mucosal injury, plus corticosteroid-induced increase in salicylate clearance.
Cosa fare
Consider a proton pump inhibitor in patients with ulcer risk factors. Monitor for GI bleeding and for salicylate toxicity when steroids are tapered at high aspirin doses.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Controindicata
- Acetylsalicylic acid + Ketorolac intranasal Controindicata
- Abciximab + Acetylsalicylic acid Maggiore
- Acemetacin + Acetylsalicylic acid Maggiore
- Acetazolamide + Acetylsalicylic acid Maggiore
- Acetylsalicylic acid + Alteplase Maggiore
Altre interazioni di Hydrocortisone
- Hydrocortisone + Mifepristone Controindicata
- Hydrocortisone + Poliovirus vaccine live oral trivalent Controindicata
- Hydrocortisone + Smallpox vaccine live Controindicata
- Adenovirus types 4 and 7 live + Hydrocortisone Maggiore
- Aldesleukin + Hydrocortisone Maggiore
Domande frequenti
Can I take Acetylsalicylic acid with Hydrocortisone?
MediHelp rates the interaction as moderate. Acetylsalicylic acid and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids combined with aspirin increase the risk of gastric ulceration and gastrointestinal bleeding. Corticosteroids may also lower salicylate levels, which can rise when the steroid is withdrawn.
How serious is the interaction between Acetylsalicylic acid and Hydrocortisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a proton pump inhibitor in patients with ulcer risk factors. Monitor for GI bleeding and for salicylate toxicity when steroids are tapered at high aspirin doses.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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