Interazioni tra farmaci
Hydrocortisone + Smallpox vaccine live
Gravità: Controindicata
Hydrocortisone and Smallpox vaccine live: contraindicated interaction.
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Sintesi
Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.
Cosa significa questa interazione in parole semplici
Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Corticosteroid-induced immunosuppression allows uncontrolled replication of live vaccinia virus.
Cosa fare
Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Hydrocortisone
- Hydrocortisone + Mifepristone Controindicata
- Hydrocortisone + Poliovirus vaccine live oral trivalent Controindicata
- Adenovirus types 4 and 7 live + Hydrocortisone Maggiore
- Aldesleukin + Hydrocortisone Maggiore
- Aspirin + Hydrocortisone Maggiore
- Bcg vaccine live + Hydrocortisone Maggiore
Domande frequenti
Can I take Hydrocortisone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.
How serious is the interaction between Hydrocortisone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Adenovirus types 4 and 7 live. The full list is on the Hydrocortisone page.
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