Interazioni tra farmaci
Hydrocortisone + Poliovirus vaccine live oral trivalent
Gravità: Controindicata
Hydrocortisone and Poliovirus vaccine live oral trivalent: contraindicated interaction.
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Sintesi
Oral polio vaccine is live attenuated and in immunosuppressed patients can cause vaccine-associated paralytic poliomyelitis. Immunosuppressive doses of hydrocortisone also reduce immune response.
Cosa significa questa interazione in parole semplici
Hydrocortisone and Poliovirus vaccine live oral trivalent are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Corticosteroid-induced immunosuppression permits prolonged replication of live attenuated poliovirus and reduces immunogenicity.
Cosa fare
Do not use live oral polio vaccine in patients on immunosuppressive corticosteroids; use inactivated polio vaccine instead. Household contacts should also preferably receive inactivated vaccine.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Hydrocortisone
- Hydrocortisone + Mifepristone Controindicata
- Hydrocortisone + Smallpox vaccine live Controindicata
- Adenovirus types 4 and 7 live + Hydrocortisone Maggiore
- Aldesleukin + Hydrocortisone Maggiore
- Aspirin + Hydrocortisone Maggiore
- Bcg vaccine live + Hydrocortisone Maggiore
Domande frequenti
Can I take Hydrocortisone with Poliovirus vaccine live oral trivalent?
MediHelp rates the interaction as contraindicated. Hydrocortisone and Poliovirus vaccine live oral trivalent are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral polio vaccine is live attenuated and in immunosuppressed patients can cause vaccine-associated paralytic poliomyelitis. Immunosuppressive doses of hydrocortisone also reduce immune response.
How serious is the interaction between Hydrocortisone and Poliovirus vaccine live oral trivalent?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use live oral polio vaccine in patients on immunosuppressive corticosteroids; use inactivated polio vaccine instead. Household contacts should also preferably receive inactivated vaccine.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Smallpox vaccine live, Adenovirus types 4 and 7 live. The full list is on the Hydrocortisone page.
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