Interazioni tra farmaci
Aluminum hydroxide + Penicillamine
Gravità: Moderata
Aluminum hydroxide and Penicillamine: moderate interaction.
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Sintesi
Aluminum-containing antacids reduce the absorption of penicillamine, which can lower its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis. The effect is clinically relevant when doses are close together.
Cosa significa questa interazione in parole semplici
Aluminum hydroxide and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
Perché avviene
Aluminum chelates or adsorbs penicillamine in the gut, reducing its oral absorption.
Cosa fare
Separate penicillamine and the antacid by at least 2 hours. Monitor clinical response, such as urinary copper or cystine, if antacids are used regularly.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Aluminum hydroxide
- Aluminum hydroxide + Ciprofloxacin Maggiore
- Aluminum hydroxide + Deferasirox Maggiore
- Aluminum hydroxide + Dolutegravir Maggiore
- Aluminum hydroxide + Raltegravir Maggiore
- Aluminum hydroxide + Rilpivirine Maggiore
- Aluminum hydroxide + Vitamin d Maggiore
Altre interazioni di Penicillamine
- Gold sodium thiomalate + Penicillamine Maggiore
- Calcium carbonate + Penicillamine Moderata
- Calcium + Penicillamine Moderata
- Carbonyl iron + Penicillamine Moderata
- Copper + Penicillamine Moderata
- Digoxin + Penicillamine Moderata
Domande frequenti
Can I take Aluminum hydroxide with Penicillamine?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum-containing antacids reduce the absorption of penicillamine, which can lower its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis. The effect is clinically relevant when doses are close together.
How serious is the interaction between Aluminum hydroxide and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate penicillamine and the antacid by at least 2 hours. Monitor clinical response, such as urinary copper or cystine, if antacids are used regularly.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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