Interazioni tra farmaci
Aminolevulinic acid + Tretinoin
Gravità: Moderata
Aminolevulinic acid and Tretinoin: moderate interaction.
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Sintesi
Oral aminolevulinic acid causes protoporphyrin IX accumulation and photosensitivity. Tretinoin can increase skin sensitivity to light, so phototoxic reactions such as severe sunburn may be worse. Systemic tretinoin is the main concern; topical use adds little.
Cosa significa questa interazione in parole semplici
Aminolevulinic acid and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aminolevulinic acid belongs to Miscellaneous; Tretinoin belongs to Dermatology.
Perché avviene
Additive photosensitizing effects from two agents that increase the skin's reactivity to light.
Cosa fare
Counsel strict photoprotection and avoid sun and bright light exposure after aminolevulinic acid for the period specified in labeling. Avoid giving other photosensitizers perioperatively around dosing.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Tretinoin
- Doxycycline + Tretinoin Maggiore
- Minocycline + Tretinoin Maggiore
- Omadacycline + Tretinoin Maggiore
- Palovarotene + Tretinoin Maggiore
- Sarecycline + Tretinoin Maggiore
- Tetracycline + Tretinoin Maggiore
Altre interazioni di Aminolevulinic acid
- Acitretin + Aminolevulinic acid Maggiore
- Aminolevulinic acid + Doxycycline Maggiore
- Aminolevulinic acid + Isotretinoin Maggiore
- Aminolevulinic acid + Amiodarone Moderata
- Aminolevulinic acid + Amlodipine-hydrochlorothiazide-valsartan Moderata
- Aminolevulinic acid + Amlodipine-olmesartan-hydrochlorothiazide Moderata
Domande frequenti
Can I take Aminolevulinic acid with Tretinoin?
MediHelp rates the interaction as moderate. Aminolevulinic acid and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral aminolevulinic acid causes protoporphyrin IX accumulation and photosensitivity. Tretinoin can increase skin sensitivity to light, so phototoxic reactions such as severe sunburn may be worse. Systemic tretinoin is the main concern; topical use adds little.
How serious is the interaction between Aminolevulinic acid and Tretinoin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict photoprotection and avoid sun and bright light exposure after aminolevulinic acid for the period specified in labeling. Avoid giving other photosensitizers perioperatively around dosing.
What other medicines interact with Tretinoin?
MediHelp also lists interactions of Tretinoin with, for example, Doxycycline, Minocycline, Omadacycline. The full list is on the Tretinoin page.
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