Interazioni tra farmaci
Amlodipine-olmesartan-hydrochlorothiazide + Colestipol
Gravità: Moderata
Amlodipine-olmesartan-hydrochlorothiazide and Colestipol: moderate interaction.
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Sintesi
Colestipol binds hydrochlorothiazide in the gut and reduces its oral absorption, which may weaken the diuretic and antihypertensive effect. Olmesartan absorption may also be reduced by bile acid sequestrants.
Cosa significa questa interazione in parole semplici
Amlodipine-olmesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Colestipol belongs to Cardiovascular.
Perché avviene
Bile acid sequestrant resin binds drugs in the gastrointestinal tract, decreasing absorption.
Cosa fare
Give the combination product at least 4 hours before colestipol, or 4 to 6 hours after it. Monitor blood pressure.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Controindicata
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Controindicata
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Controindicata
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Maggiore
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Maggiore
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Maggiore
Altre interazioni di Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderata
- Atenolol-chlorthalidone + Colestipol Moderata
- Azilsartan-chlorthalidone + Colestipol Moderata
- Candesartan-hydrochlorothiazide + Colestipol Moderata
- Captopril-hydrochlorothiazide + Colestipol Moderata
- Chenodeoxycholic acid + Colestipol Moderata
Domande frequenti
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Colestipol?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol binds hydrochlorothiazide in the gut and reduces its oral absorption, which may weaken the diuretic and antihypertensive effect. Olmesartan absorption may also be reduced by bile acid sequestrants.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the combination product at least 4 hours before colestipol, or 4 to 6 hours after it. Monitor blood pressure.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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