Interazioni tra farmaci
Candesartan-hydrochlorothiazide + Colestipol
Gravità: Moderata
Candesartan-hydrochlorothiazide and Colestipol: moderate interaction.
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Sintesi
Colestipol binds hydrochlorothiazide in the gut and reduces its absorption, which can blunt the diuretic and antihypertensive effect. The effect is dose-timing dependent and can be avoided by separating administration.
Cosa significa questa interazione in parole semplici
Candesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Candesartan-hydrochlorothiazide belongs to Cardiovascular; Colestipol belongs to Cardiovascular.
Perché avviene
Bile acid sequestrant binds hydrochlorothiazide in the gastrointestinal tract, reducing absorption.
Cosa fare
Give hydrochlorothiazide at least 4 hours before or after colestipol, and monitor blood pressure.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Candesartan-hydrochlorothiazide
- Aliskiren + Candesartan-hydrochlorothiazide Controindicata
- Candesartan-hydrochlorothiazide + Dofetilide Controindicata
- Candesartan-hydrochlorothiazide + Sparsentan Controindicata
- Acemetacin + Candesartan-hydrochlorothiazide Maggiore
- Amifostine + Candesartan-hydrochlorothiazide Maggiore
- Amiloride + Candesartan-hydrochlorothiazide Maggiore
Altre interazioni di Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderata
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderata
- Atenolol-chlorthalidone + Colestipol Moderata
- Azilsartan-chlorthalidone + Colestipol Moderata
- Captopril-hydrochlorothiazide + Colestipol Moderata
- Chenodeoxycholic acid + Colestipol Moderata
Domande frequenti
Can I take Candesartan-hydrochlorothiazide with Colestipol?
MediHelp rates the interaction as moderate. Candesartan-hydrochlorothiazide and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol binds hydrochlorothiazide in the gut and reduces its absorption, which can blunt the diuretic and antihypertensive effect. The effect is dose-timing dependent and can be avoided by separating administration.
How serious is the interaction between Candesartan-hydrochlorothiazide and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give hydrochlorothiazide at least 4 hours before or after colestipol, and monitor blood pressure.
What other medicines interact with Candesartan-hydrochlorothiazide?
MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.
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