Interazioni tra farmaci
Amyl nitrite + Vardenafil
Gravità: Controindicata
Amyl nitrite and Vardenafil: contraindicated interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Vardenafil greatly enhances the vasodilator effect of nitrates such as amyl nitrite. This can cause severe, potentially fatal hypotension.
Cosa significa questa interazione in parole semplici
Amyl nitrite and Vardenafil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Nitrates increase cGMP through nitric oxide and vardenafil inhibits its degradation by PDE5, causing excessive vasodilation.
Cosa fare
Do not co-administer, including recreational nitrite inhalants. Keep a safe interval, at least 24 hours, before any nitrate is given after vardenafil.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Amyl nitrite e Vardenafil, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Vardenafil
- Glyceryl trinitrate pr + Vardenafil Controindicata
- Isosorbide dinitrate + Vardenafil Controindicata
- Isosorbide mononitrate + Vardenafil Controindicata
- Nicorandil + Vardenafil Controindicata
- Nitroglycerin po + Vardenafil Controindicata
- Nitroglycerin rectal + Vardenafil Controindicata
Domande frequenti
Can I take Amyl nitrite with Vardenafil?
MediHelp rates the interaction as contraindicated. Amyl nitrite and Vardenafil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vardenafil greatly enhances the vasodilator effect of nitrates such as amyl nitrite. This can cause severe, potentially fatal hypotension.
How serious is the interaction between Amyl nitrite and Vardenafil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer, including recreational nitrite inhalants. Keep a safe interval, at least 24 hours, before any nitrate is given after vardenafil.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Glyceryl trinitrate pr, Isosorbide dinitrate, Isosorbide mononitrate. The full list is on the Vardenafil page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
