Interazioni tra farmaci
Aspirin / citric acid / sodium bicarbonate + Ketorolac
Gravità: Controindicata
Aspirin / citric acid / sodium bicarbonate and Ketorolac: contraindicated interaction.
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Sintesi
Ketorolac labeling contraindicates use with aspirin and other NSAIDs. The effervescent aspirin product delivers analgesic-dose aspirin, so bleeding, ulcer and renal risks are additive.
Cosa significa questa interazione in parole semplici
Aspirin / citric acid / sodium bicarbonate and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive cyclooxygenase inhibition causing GI mucosal injury, platelet inhibition and reduced renal prostaglandins.
Cosa fare
Do not use together. Choose a non-NSAID analgesic such as paracetamol instead of one of the agents.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Ketorolac
- Aceclofenac + Ketorolac Controindicata
- Acemetacin + Ketorolac Controindicata
- Acetylsalicylic acid + Ketorolac Controindicata
- Apixaban + Ketorolac Controindicata
- Argatroban + Ketorolac Controindicata
- Aspirin rectal + Ketorolac Controindicata
Domande frequenti
Can I take Aspirin / citric acid / sodium bicarbonate with Ketorolac?
MediHelp rates the interaction as contraindicated. Aspirin / citric acid / sodium bicarbonate and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac labeling contraindicates use with aspirin and other NSAIDs. The effervescent aspirin product delivers analgesic-dose aspirin, so bleeding, ulcer and renal risks are additive.
How serious is the interaction between Aspirin / citric acid / sodium bicarbonate and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Choose a non-NSAID analgesic such as paracetamol instead of one of the agents.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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