Interazioni tra farmaci
Atomoxetine + Procarbazine
Gravità: Controindicata
Atomoxetine and Procarbazine: contraindicated interaction.
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Sintesi
Procarbazine inhibits monoamine oxidase, and atomoxetine raises synaptic noradrenaline. The combination has led to hypertensive reactions, hyperthermia, rigidity and altered consciousness.
Cosa significa questa interazione in parole semplici
Atomoxetine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Atomoxetine belongs to Central Nervous System; Procarbazine belongs to Oncology.
Perché avviene
MAO inhibition plus noradrenaline reuptake inhibition causes excessive adrenergic stimulation
Cosa fare
Do not use together; wait at least 14 days after stopping a MAOI before starting atomoxetine, and 2 days the other way round.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Atomoxetine
- Atomoxetine + Isocarboxazid Controindicata
- Atomoxetine + Linezolid Controindicata
- Atomoxetine + Phenelzine Controindicata
- Atomoxetine + Rasagiline Controindicata
- Atomoxetine + Selegiline Controindicata
- Atomoxetine + Selegiline transdermal Controindicata
Altre interazioni di Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Controindicata
- Amitriptyline + Procarbazine Controindicata
- Amoxapine + Procarbazine Controindicata
- Bcg vaccine live + Procarbazine Controindicata
- Brimonidine + Procarbazine Controindicata
- Buspirone + Procarbazine Controindicata
Domande frequenti
Can I take Atomoxetine with Procarbazine?
MediHelp rates the interaction as contraindicated. Atomoxetine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Procarbazine inhibits monoamine oxidase, and atomoxetine raises synaptic noradrenaline. The combination has led to hypertensive reactions, hyperthermia, rigidity and altered consciousness.
How serious is the interaction between Atomoxetine and Procarbazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; wait at least 14 days after stopping a MAOI before starting atomoxetine, and 2 days the other way round.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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