Interazioni tra farmaci
Atomoxetine + Isocarboxazid
Gravità: Controindicata
Atomoxetine and Isocarboxazid: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Isocarboxazid inhibits monoamine oxidase, and atomoxetine raises synaptic noradrenaline. The combination has led to hypertensive reactions, hyperthermia, rigidity and altered consciousness.
Cosa significa questa interazione in parole semplici
Atomoxetine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Atomoxetine belongs to Central Nervous System; Isocarboxazid belongs to Central Nervous System.
Perché avviene
MAO inhibition plus noradrenaline reuptake inhibition causes excessive adrenergic stimulation
Cosa fare
Do not use together; wait at least 14 days after stopping a MAOI before starting atomoxetine, and 2 days the other way round.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Atomoxetine
- Atomoxetine + Linezolid Controindicata
- Atomoxetine + Phenelzine Controindicata
- Atomoxetine + Procarbazine Controindicata
- Atomoxetine + Rasagiline Controindicata
- Atomoxetine + Selegiline Controindicata
- Atomoxetine + Selegiline transdermal Controindicata
Altre interazioni di Isocarboxazid
- 5-HTP + Isocarboxazid Controindicata
- Amitriptyline + Isocarboxazid Controindicata
- Amobarbital + Isocarboxazid Controindicata
- Amoxapine + Isocarboxazid Controindicata
- Apraclonidine + Isocarboxazid Controindicata
- Benzphetamine + Isocarboxazid Controindicata
Domande frequenti
Can I take Atomoxetine with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Atomoxetine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Isocarboxazid inhibits monoamine oxidase, and atomoxetine raises synaptic noradrenaline. The combination has led to hypertensive reactions, hyperthermia, rigidity and altered consciousness.
How serious is the interaction between Atomoxetine and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; wait at least 14 days after stopping a MAOI before starting atomoxetine, and 2 days the other way round.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Linezolid, Phenelzine, Procarbazine. The full list is on the Atomoxetine page.
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