Interazioni tra farmaci
Azathioprine + Bcg vaccine live
Gravità: Controindicata
Azathioprine and Bcg vaccine live: contraindicated interaction.
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Sintesi
BCG is a live attenuated bacterial vaccine and can cause disseminated BCG infection in immunosuppressed patients. Azathioprine impairs the cellular immunity needed to contain it.
Cosa significa questa interazione in parole semplici
Azathioprine and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Azathioprine-induced suppression of T-cell function allows uncontrolled replication of live attenuated Mycobacterium bovis.
Cosa fare
Do not give BCG to patients on azathioprine; defer until immunosuppression has been stopped for the interval recommended by local guidance. Assess tuberculosis risk by alternative means.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine Controindicata
- Azathioprine + Febuxostat Controindicata
- Azathioprine + Influenza virus vaccine quadrivalent intranasal Controindicata
- Azathioprine + Measles mumps and rubella vaccine Controindicata
- Azathioprine + Measles mumps and rubella vaccine live Controindicata
- Azathioprine + Measles mumps rubella and varicella vaccine live Controindicata
Domande frequenti
Can I take Azathioprine with Bcg vaccine live?
MediHelp rates the interaction as contraindicated. Azathioprine and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated bacterial vaccine and can cause disseminated BCG infection in immunosuppressed patients. Azathioprine impairs the cellular immunity needed to contain it.
How serious is the interaction between Azathioprine and Bcg vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients on azathioprine; defer until immunosuppression has been stopped for the interval recommended by local guidance. Assess tuberculosis risk by alternative means.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Febuxostat, Influenza virus vaccine quadrivalent intranasal. The full list is on the Azathioprine page.
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