Interazioni tra farmaci
Azelastine + Dexchlorpheniramine
Gravità: Moderata
Azelastine and Dexchlorpheniramine: moderate interaction.
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Sintesi
Both are H1 antihistamines, and dexchlorpheniramine is sedating and anticholinergic. Combined use duplicates therapy and increases drowsiness and anticholinergic effects.
Cosa significa questa interazione in parole semplici
Azelastine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azelastine belongs to Respiratory; Dexchlorpheniramine belongs to Respiratory.
Perché avviene
Duplicate H1 antagonism producing additive sedation and anticholinergic effects.
Cosa fare
Avoid concurrent use and choose one antihistamine. If unavoidable, monitor for sedation and anticholinergic effects.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Azelastine
- Azelastine + Calcium / magnesium / potassium / sodium oxybates Maggiore
- Azelastine + Methadone Maggiore
- Azelastine + Sodium oxybate Maggiore
- Alfentanil + Azelastine Moderata
- Alprazolam + Azelastine Moderata
- Amitriptyline + Azelastine Moderata
Altre interazioni di Dexchlorpheniramine
- Alprazolam + Dexchlorpheniramine Moderata
- Amisulpride + Dexchlorpheniramine Moderata
- Amitriptyline + Dexchlorpheniramine Moderata
- Amobarbital + Dexchlorpheniramine Moderata
- Asenapine + Dexchlorpheniramine Moderata
- Azelastine-fluticasone + Dexchlorpheniramine Moderata
Domande frequenti
Can I take Azelastine with Dexchlorpheniramine?
MediHelp rates the interaction as moderate. Azelastine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are H1 antihistamines, and dexchlorpheniramine is sedating and anticholinergic. Combined use duplicates therapy and increases drowsiness and anticholinergic effects.
How serious is the interaction between Azelastine and Dexchlorpheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose one antihistamine. If unavoidable, monitor for sedation and anticholinergic effects.
What other medicines interact with Azelastine?
MediHelp also lists interactions of Azelastine with, for example, Calcium / magnesium / potassium / sodium oxybates, Methadone, Sodium oxybate. The full list is on the Azelastine page.
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