Interazioni tra farmaci
Baricitinib + Bcg vaccine live
Gravità: Controindicata
Baricitinib and Bcg vaccine live: contraindicated interaction.
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Sintesi
Baricitinib-related immunosuppression raises the risk of disseminated BCG infection from the live vaccine and may reduce its effectiveness.
Cosa significa questa interazione in parole semplici
Baricitinib and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
JAK inhibition-induced immunosuppression allows uncontrolled replication of live attenuated bacteria.
Cosa fare
Do not give BCG vaccine during baricitinib treatment. Vaccinate before starting therapy where indicated, following current guidelines.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Baricitinib
- Adenovirus types 4 and 7 live + Baricitinib Controindicata
- Baricitinib + Tofacitinib Controindicata
- Baricitinib + Upadacitinib Controindicata
- Abatacept + Baricitinib Maggiore
- Adalimumab + Baricitinib Maggiore
- Ado-trastuzumab + Baricitinib Maggiore
Domande frequenti
Can I take Baricitinib with Bcg vaccine live?
MediHelp rates the interaction as contraindicated. Baricitinib and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Baricitinib-related immunosuppression raises the risk of disseminated BCG infection from the live vaccine and may reduce its effectiveness.
How serious is the interaction between Baricitinib and Bcg vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG vaccine during baricitinib treatment. Vaccinate before starting therapy where indicated, following current guidelines.
What other medicines interact with Baricitinib?
MediHelp also lists interactions of Baricitinib with, for example, Adenovirus types 4 and 7 live, Tofacitinib, Upadacitinib. The full list is on the Baricitinib page.
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