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Interazioni tra farmaci

Bcg vaccine live + Cefaclor

Gravità: Moderata

Bcg vaccine live and Cefaclor: moderate interaction.

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Sintesi

Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host. Cefaclor has little expected activity against BCG, so the effect is largely theoretical.

Cosa significa questa interazione in parole semplici

Bcg vaccine live and Cefaclor can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Livello di evidenza: Low

Perché avviene

Antibacterial activity could reduce replication of the live attenuated organism, though cephalosporin activity against BCG is limited.

Cosa fare

Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of cefaclor.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Bcg vaccine live with Cefaclor?

MediHelp rates the interaction as moderate. Bcg vaccine live and Cefaclor can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host. Cefaclor has little expected activity against BCG, so the effect is largely theoretical.

How serious is the interaction between Bcg vaccine live and Cefaclor?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of cefaclor.

What other medicines interact with Cefaclor?

MediHelp also lists interactions of Cefaclor with, for example, Cholera vaccine, Kanamycin, Microbiota. The full list is on the Cefaclor page.

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