Interazioni tra farmaci
Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid
Gravità: Moderata
Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
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Sintesi
Sodium picosulfate is a prodrug that needs colonic bacteria to form its active laxative metabolite. Antibiotics given before bowel preparation may reduce this conversion and result in inadequate bowel cleansing before colonoscopy.
Cosa significa questa interazione in parole semplici
Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Antibiotic suppression of colonic bacteria that convert sodium picosulfate to its active metabolite.
Cosa fare
Where possible, avoid starting the antibiotic before the preparation, or complete the course earlier. Confirm adequate bowel cleansing before the procedure.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefaclor
- Bcg vaccine live + Cefaclor Moderata
- Cefaclor + Cholera vaccine Moderata
- Cefaclor + Kanamycin Moderata
- Cefaclor + Microbiota Moderata
- Cefaclor + Plazomicin Moderata
- Cefaclor + Typhoid vaccine live Moderata
Domande frequenti
Can I take Cefaclor with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that needs colonic bacteria to form its active laxative metabolite. Antibiotics given before bowel preparation may reduce this conversion and result in inadequate bowel cleansing before colonoscopy.
How serious is the interaction between Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, avoid starting the antibiotic before the preparation, or complete the course earlier. Confirm adequate bowel cleansing before the procedure.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
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