Interazioni tra farmaci
Cefaclor + Cholera vaccine
Gravità: Moderata
Cefaclor and Cholera vaccine: moderate interaction.
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Sintesi
The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response. Cefaclor activity against Vibrio cholerae is uncertain, but labeling advises caution with antibiotics in general.
Cosa significa questa interazione in parole semplici
Cefaclor and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Antibacterial activity may inhibit replication of the live attenuated vaccine strain, lowering immunogenicity.
Cosa fare
Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefaclor
- Bcg vaccine live + Cefaclor Moderata
- Cefaclor + Kanamycin Moderata
- Cefaclor + Microbiota Moderata
- Cefaclor + Plazomicin Moderata
- Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderata
- Cefaclor + Typhoid vaccine live Moderata
Domande frequenti
Can I take Cefaclor with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefaclor and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response. Cefaclor activity against Vibrio cholerae is uncertain, but labeling advises caution with antibiotics in general.
How serious is the interaction between Cefaclor and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Kanamycin, Microbiota. The full list is on the Cefaclor page.
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