Drug interactions
Bcg vaccine live + Golimumab
Severity: Contraindicated
Bcg vaccine live and Golimumab: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
BCG vaccine contains live attenuated mycobacteria. In golimumab-treated patients, impaired granuloma function may allow disseminated BCG infection.
What this interaction means in plain words
Bcg vaccine live and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
TNF is essential for granuloma formation and mycobacterial containment, so its blockade permits BCG dissemination.
What to do
Do not give BCG during golimumab therapy. If needed, vaccinate at least 4 weeks before starting treatment.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Golimumab
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
- Golimumab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Bcg vaccine live with Golimumab?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG vaccine contains live attenuated mycobacteria. In golimumab-treated patients, impaired granuloma function may allow disseminated BCG infection.
How serious is the interaction between Bcg vaccine live and Golimumab?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during golimumab therapy. If needed, vaccinate at least 4 weeks before starting treatment.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Etanercept, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Golimumab page.
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