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Interazioni tra farmaci

Bcg vaccine live + Mycophenolate mofetil

Gravità: Controindicata

Bcg vaccine live and Mycophenolate mofetil: contraindicated interaction.

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Sintesi

Live BCG can cause disseminated BCG infection in patients taking mycophenolate, and the vaccine response may be reduced. Live vaccines are contraindicated in significantly immunosuppressed patients.

Cosa significa questa interazione in parole semplici

Bcg vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: Moderate

Perché avviene

Mycophenolate impairs lymphocyte-mediated control of live attenuated mycobacteria and blunts vaccine response.

Cosa fare

Do not give BCG vaccine during mycophenolate therapy; consider alternative TB prevention strategies and screening.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Bcg vaccine live with Mycophenolate mofetil?

MediHelp rates the interaction as contraindicated. Bcg vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live BCG can cause disseminated BCG infection in patients taking mycophenolate, and the vaccine response may be reduced. Live vaccines are contraindicated in significantly immunosuppressed patients.

How serious is the interaction between Bcg vaccine live and Mycophenolate mofetil?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG vaccine during mycophenolate therapy; consider alternative TB prevention strategies and screening.

What other medicines interact with Mycophenolate mofetil?

MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Mycophenolate mofetil page.

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