Interazioni tra farmaci
Mycophenolate mofetil + Rotavirus oral vaccine live
Gravità: Controindicata
Mycophenolate mofetil and Rotavirus oral vaccine live: contraindicated interaction.
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Sintesi
Rotavirus vaccine is live attenuated, and replication may be prolonged or cause disease in patients with significant immunosuppression. Mycophenolate exposure, including in infants born to treated mothers, raises this concern.
Cosa significa questa interazione in parole semplici
Mycophenolate mofetil and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Impaired immune control allows replication of live attenuated rotavirus.
Cosa fare
Avoid the live vaccine in patients on mycophenolate. For infants exposed in utero, follow specialist advice on timing.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Controindicata
- Bcg vaccine live + Mycophenolate mofetil Controindicata
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Controindicata
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Controindicata
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Controindicata
- Measles vaccine + Mycophenolate mofetil Controindicata
Domande frequenti
Can I take Mycophenolate mofetil with Rotavirus oral vaccine live?
MediHelp rates the interaction as contraindicated. Mycophenolate mofetil and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rotavirus vaccine is live attenuated, and replication may be prolonged or cause disease in patients with significant immunosuppression. Mycophenolate exposure, including in infants born to treated mothers, raises this concern.
How serious is the interaction between Mycophenolate mofetil and Rotavirus oral vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live vaccine in patients on mycophenolate. For infants exposed in utero, follow specialist advice on timing.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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