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Interazioni tra farmaci

Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil

Gravità: Controindicata

Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil: contraindicated interaction.

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Sintesi

This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.

Cosa significa questa interazione in parole semplici

Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: High

Perché avviene

Mycophenolate-induced lymphocyte suppression permits replication of live attenuated viruses.

Cosa fare

Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Measles mumps rubella and varicella vaccine live with Mycophenolate mofetil?

MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.

How serious is the interaction between Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.

What other medicines interact with Mycophenolate mofetil?

MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.

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