Interazioni tra farmaci
Belladonna alkaloids + Umeclidinium
Gravità: Moderata
Belladonna alkaloids and Umeclidinium: moderate interaction.
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Sintesi
Belladonna alkaloids such as atropine, hyoscyamine and scopolamine are antimuscarinic and add to the effects of umeclidinium. This can cause dry mouth, constipation, urinary retention, tachycardia and confusion in older adults.
Cosa significa questa interazione in parole semplici
Belladonna alkaloids and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Additive muscarinic receptor antagonism.
Cosa fare
Avoid concurrent use where an alternative exists. If needed, monitor for urinary retention, constipation and CNS effects, particularly in older patients.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Umeclidinium
- Tiotropium + Umeclidinium Maggiore
- Aclidinium + Umeclidinium Moderata
- Atropine iv / + Umeclidinium Moderata
- Atropine + Umeclidinium Moderata
- Bethanechol + Umeclidinium Moderata
- Dicyclomine + Umeclidinium Moderata
Domande frequenti
Can I take Belladonna alkaloids with Umeclidinium?
MediHelp rates the interaction as moderate. Belladonna alkaloids and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belladonna alkaloids such as atropine, hyoscyamine and scopolamine are antimuscarinic and add to the effects of umeclidinium. This can cause dry mouth, constipation, urinary retention, tachycardia and confusion in older adults.
How serious is the interaction between Belladonna alkaloids and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where an alternative exists. If needed, monitor for urinary retention, constipation and CNS effects, particularly in older patients.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
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