Interazioni tra farmaci
Bictegravir + Ferrous sulfate
Gravità: Moderata
Bictegravir and Ferrous sulfate: moderate interaction.
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Sintesi
Iron binds bictegravir in the gut and can lower its absorption, risking reduced antiviral activity and resistance. The effect is largely avoided when both are taken together with food.
Cosa significa questa interazione in parole semplici
Bictegravir and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Chelation of bictegravir by polyvalent iron cations in the gastrointestinal tract reduces absorption.
Cosa fare
Take bictegravir and iron together with food, or give bictegravir at least 2 hours before iron when fasting. Do not take it fasting at the same time as, or within 2 hours after, iron.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Ferrous sulfate
- Ciprofloxacin + Ferrous sulfate Maggiore
- Dimercaprol + Ferrous sulfate Maggiore
- Acetohydroxamic acid + Ferrous sulfate Moderata
- Aluminum hydroxide + Ferrous sulfate Moderata
- Baloxavir marboxil + Ferrous sulfate Moderata
- Calcium carbonate + Ferrous sulfate Moderata
Domande frequenti
Can I take Bictegravir with Ferrous sulfate?
MediHelp rates the interaction as moderate. Bictegravir and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds bictegravir in the gut and can lower its absorption, risking reduced antiviral activity and resistance. The effect is largely avoided when both are taken together with food.
How serious is the interaction between Bictegravir and Ferrous sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take bictegravir and iron together with food, or give bictegravir at least 2 hours before iron when fasting. Do not take it fasting at the same time as, or within 2 hours after, iron.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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