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Dimercaprol + Ferrous sulfate

Gravità: Maggiore

Dimercaprol and Ferrous sulfate: major interaction.

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Sintesi

Dimercaprol forms toxic complexes with iron and is not recommended in iron poisoning. The resulting iron-dimercaprol complex can be harmful to the kidneys and is of no benefit for iron removal. Oral iron should not be given with dimercaprol during chelation therapy.

Cosa significa questa interazione in parole semplici

Dimercaprol and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Livello di evidenza: Moderate

Perché avviene

Dimercaprol forms a chelate with iron that is toxic and may worsen toxicity rather than promoting safe elimination.

Cosa fare

Do not use dimercaprol to treat iron overload or iron poisoning; use deferoxamine instead. Hold iron supplements while dimercaprol is being given.

Cosa chiedere al farmacista

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Dimercaprol with Ferrous sulfate?

MediHelp rates the interaction as major. Dimercaprol and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dimercaprol forms toxic complexes with iron and is not recommended in iron poisoning. The resulting iron-dimercaprol complex can be harmful to the kidneys and is of no benefit for iron removal. Oral iron should not be given with dimercaprol during chelation therapy.

How serious is the interaction between Dimercaprol and Ferrous sulfate?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use dimercaprol to treat iron overload or iron poisoning; use deferoxamine instead. Hold iron supplements while dimercaprol is being given.

What other medicines interact with Ferrous sulfate?

MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous sulfate page.

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