Interazioni tra farmaci
Ciprofloxacin + Ferrous sulfate
Gravità: Maggiore
Ciprofloxacin and Ferrous sulfate: major interaction.
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Sintesi
Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
Cosa significa questa interazione in parole semplici
Ciprofloxacin and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Ferrous sulfate belongs to Miscellaneous.
Perché avviene
Ferrous iron chelates ciprofloxacin in the gastrointestinal tract, forming poorly absorbed complexes.
Cosa fare
Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
Cosa chiedere al farmacista
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Altre interazioni di Ciprofloxacin
- Agomelatine + Ciprofloxacin Controindicata
- Ciprofloxacin + Fezolinetant Controindicata
- Ciprofloxacin + Thioridazine Controindicata
- Ciprofloxacin + Tizanidine Controindicata
- Ciprofloxacin + Vandetanib Controindicata
- Alosetron + Ciprofloxacin Maggiore
Altre interazioni di Ferrous sulfate
- Dimercaprol + Ferrous sulfate Maggiore
- Acetohydroxamic acid + Ferrous sulfate Moderata
- Aluminum hydroxide + Ferrous sulfate Moderata
- Baloxavir marboxil + Ferrous sulfate Moderata
- Bictegravir + Ferrous sulfate Moderata
- Calcium carbonate + Ferrous sulfate Moderata
Domande frequenti
Can I take Ciprofloxacin with Ferrous sulfate?
MediHelp rates the interaction as major. Ciprofloxacin and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
How serious is the interaction between Ciprofloxacin and Ferrous sulfate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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