Interazioni tra farmaci
Cefazolin + Microbiota
Gravità: Moderata
Cefazolin and Microbiota: moderate interaction.
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Sintesi
Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
Cosa significa questa interazione in parole semplici
Cefazolin and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Antibacterial activity against the live bacterial components of the product reduces colonization (pharmacodynamic antagonism).
Cosa fare
Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefazolin
- Amikacin + Cefazolin Moderata
- Bcg vaccine live + Cefazolin Moderata
- Cefazolin + Cholera vaccine Moderata
- Cefazolin + Dexamethasone-tobramycin Moderata
- Cefazolin + Gentamicin Moderata
- Cefazolin + Kanamycin Moderata
Domande frequenti
Can I take Cefazolin with Microbiota?
MediHelp rates the interaction as moderate. Cefazolin and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
How serious is the interaction between Cefazolin and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
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