Interazioni tra farmaci
Cefotaxime + Sodium picosulfate / magnesium oxide / anhydrous citric acid
Gravità: Moderata
Cefotaxime and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
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Sintesi
Sodium picosulfate is a prodrug that requires colonic bacteria to be converted to its active laxative form. Antibacterials can suppress this flora and may lead to a weaker bowel-cleansing effect before colonoscopy.
Cosa significa questa interazione in parole semplici
Cefotaxime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Antibiotic suppression of colonic bacteria reduces conversion of sodium picosulfate to its active metabolite.
Cosa fare
Avoid giving the antibiotic during the bowel preparation period where possible. If the antibiotic is essential, confirm adequate bowel cleansing before the procedure.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefotaxime
- Cefotaxime + Typhoid vaccine live Maggiore
- Amikacin + Cefotaxime Moderata
- Cefotaxime + Cholera vaccine Moderata
- Cefotaxime + Dexamethasone-tobramycin Moderata
- Cefotaxime + Gentamicin Moderata
- Cefotaxime + Kanamycin Moderata
Domande frequenti
Can I take Cefotaxime with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Cefotaxime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that requires colonic bacteria to be converted to its active laxative form. Antibacterials can suppress this flora and may lead to a weaker bowel-cleansing effect before colonoscopy.
How serious is the interaction between Cefotaxime and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the antibiotic during the bowel preparation period where possible. If the antibiotic is essential, confirm adequate bowel cleansing before the procedure.
What other medicines interact with Cefotaxime?
MediHelp also lists interactions of Cefotaxime with, for example, Typhoid vaccine live, Amikacin, Cholera vaccine. The full list is on the Cefotaxime page.
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