Interazioni tra farmaci
Colestipol + Niacin
Gravità: Moderata
Colestipol and Niacin: moderate interaction.
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Sintesi
Colestipol is a bile acid sequestrant that can bind niacin in the gut and reduce how much is absorbed. This may blunt the lipid-lowering effect of niacin. The two are sometimes used together deliberately, so the practical effect is usually modest.
Cosa significa questa interazione in parole semplici
Colestipol and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colestipol belongs to Cardiovascular; Niacin belongs to Cardiovascular.
Perché avviene
Colestipol binds niacin in the gastrointestinal lumen and reduces its oral absorption.
Cosa fare
Give niacin at least 1 hour before or 4 hours after colestipol. Monitor the lipid profile and adjust the niacin dose if the response is inadequate.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Niacin
- Alogliptin-metformin + Niacin Moderata
- Atorvastatin + Niacin Moderata
- Canagliflozin-metformin + Niacin Moderata
- Cholestyramine + Niacin Moderata
- Dapagliflozin-metformin + Niacin Moderata
- Empagliflozin-metformin + Niacin Moderata
Altre interazioni di Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderata
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderata
- Atenolol-chlorthalidone + Colestipol Moderata
- Azilsartan-chlorthalidone + Colestipol Moderata
- Candesartan-hydrochlorothiazide + Colestipol Moderata
- Captopril-hydrochlorothiazide + Colestipol Moderata
Domande frequenti
Can I take Colestipol with Niacin?
MediHelp rates the interaction as moderate. Colestipol and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that can bind niacin in the gut and reduce how much is absorbed. This may blunt the lipid-lowering effect of niacin. The two are sometimes used together deliberately, so the practical effect is usually modest.
How serious is the interaction between Colestipol and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give niacin at least 1 hour before or 4 hours after colestipol. Monitor the lipid profile and adjust the niacin dose if the response is inadequate.
What other medicines interact with Niacin?
MediHelp also lists interactions of Niacin with, for example, Alogliptin-metformin, Atorvastatin, Canagliflozin-metformin. The full list is on the Niacin page.
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