Interazioni tra farmaci
Cyclizine + Glycopyrrolate
Gravità: Moderata
Cyclizine and Glycopyrrolate: moderate interaction.
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Sintesi
Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.
Cosa significa questa interazione in parole semplici
Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cyclizine belongs to Respiratory; Glycopyrrolate belongs to Respiratory.
Perché avviene
Additive muscarinic receptor antagonism.
Cosa fare
Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cyclizine
- Calcium / magnesium / potassium / sodium oxybates + Cyclizine Maggiore
- Cyclizine + Henbane Maggiore
- Cyclizine + Sodium oxybate Maggiore
- Abobotulinumtoxina + Cyclizine Moderata
- Alfentanil + Cyclizine Moderata
- Alprazolam + Cyclizine Moderata
Altre interazioni di Glycopyrrolate
- Glycopyrrolate + Potassium chloride Maggiore
- Amitriptyline + Glycopyrrolate Moderata
- Atropine + Glycopyrrolate Moderata
- Bethanechol + Glycopyrrolate Moderata
- Chlorpromazine + Glycopyrrolate Moderata
- Clomipramine + Glycopyrrolate Moderata
Domande frequenti
Can I take Cyclizine with Glycopyrrolate?
MediHelp rates the interaction as moderate. Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.
How serious is the interaction between Cyclizine and Glycopyrrolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Henbane, Sodium oxybate. The full list is on the Cyclizine page.
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