Interazioni tra farmaci
Deflazacort + Measles mumps rubella and varicella vaccine live
Gravità: Controindicata
Deflazacort and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.
Cosa significa questa interazione in parole semplici
Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Glucocorticoid immunosuppression impairs control of live attenuated viruses and reduces vaccine immunogenicity.
Cosa fare
Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Controindicata
- Bcg vaccine live + Deflazacort Controindicata
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Controindicata
- Deflazacort + Measles mumps and rubella vaccine Controindicata
- Deflazacort + Measles mumps and rubella vaccine live Controindicata
- Deflazacort + Measles vaccine Controindicata
Domande frequenti
Can I take Deflazacort with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.
How serious is the interaction between Deflazacort and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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