Interazioni tra farmaci
Demeclocycline + Isotretinoin
Gravità: Controindicata
Demeclocycline and Isotretinoin: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Both isotretinoin and tetracyclines such as demeclocycline can independently cause raised intracranial pressure. Combined use increases the risk of pseudotumor cerebri, with headache, visual disturbance and papilledema, and potential permanent vision loss.
Cosa significa questa interazione in parole semplici
Demeclocycline and Isotretinoin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive pharmacodynamic effect on intracranial pressure; exact mechanism not established.
Cosa fare
Avoid concurrent use; choose a non-tetracycline antibiotic. If headache or visual symptoms develop, stop both and obtain urgent ophthalmologic evaluation.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Isotretinoin
- Isotretinoin + Minocycline Controindicata
- Isotretinoin + Oxytetracycline Controindicata
- Isotretinoin + Palovarotene Controindicata
- Aminolevulinic acid + Isotretinoin Maggiore
- Doxycycline + Isotretinoin Maggiore
- Isotretinoin + Lomitapide Maggiore
Domande frequenti
Can I take Demeclocycline with Isotretinoin?
MediHelp rates the interaction as contraindicated. Demeclocycline and Isotretinoin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both isotretinoin and tetracyclines such as demeclocycline can independently cause raised intracranial pressure. Combined use increases the risk of pseudotumor cerebri, with headache, visual disturbance and papilledema, and potential permanent vision loss.
How serious is the interaction between Demeclocycline and Isotretinoin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; choose a non-tetracycline antibiotic. If headache or visual symptoms develop, stop both and obtain urgent ophthalmologic evaluation.
What other medicines interact with Isotretinoin?
MediHelp also lists interactions of Isotretinoin with, for example, Minocycline, Oxytetracycline, Palovarotene. The full list is on the Isotretinoin page.
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