Interazioni tra farmaci
Desloratadine + Tranylcypromine
Gravità: Moderata
Desloratadine and Tranylcypromine: moderate interaction.
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Sintesi
MAO inhibitors may intensify and prolong the anticholinergic and sedative effects of antihistamines. Desloratadine is non-sedating at usual doses, so the effect is generally mild.
Cosa significa questa interazione in parole semplici
Desloratadine and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desloratadine belongs to Respiratory; Tranylcypromine belongs to Central Nervous System.
Perché avviene
Additive pharmacodynamic CNS depression, with MAO inhibition possibly potentiating antihistamine anticholinergic effects.
Cosa fare
Monitor for drowsiness and anticholinergic symptoms such as dry mouth or urinary retention. Advise caution with driving until the response is known.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Desloratadine
- Desloratadine + Erdafitinib Moderata
- Desloratadine + Isocarboxazid Moderata
- Desloratadine + Zuranolone Moderata
- Amifampridine + Desloratadine Minore
- Berotralstat + Desloratadine Minore
- Bosutinib + Desloratadine Minore
Altre interazioni di Tranylcypromine
- 5-HTP + Tranylcypromine Controindicata
- Amitriptyline + Tranylcypromine Controindicata
- Amoxapine + Tranylcypromine Controindicata
- Atomoxetine + Tranylcypromine Controindicata
- Benzphetamine + Tranylcypromine Controindicata
- Brimonidine + Tranylcypromine Controindicata
Domande frequenti
Can I take Desloratadine with Tranylcypromine?
MediHelp rates the interaction as moderate. Desloratadine and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. MAO inhibitors may intensify and prolong the anticholinergic and sedative effects of antihistamines. Desloratadine is non-sedating at usual doses, so the effect is generally mild.
How serious is the interaction between Desloratadine and Tranylcypromine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for drowsiness and anticholinergic symptoms such as dry mouth or urinary retention. Advise caution with driving until the response is known.
What other medicines interact with Desloratadine?
MediHelp also lists interactions of Desloratadine with, for example, Erdafitinib, Isocarboxazid, Zuranolone. The full list is on the Desloratadine page.
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