Interazioni tra farmaci
Dexamethasone + Smallpox vaccine live
Gravità: Controindicata
Dexamethasone and Smallpox vaccine live: contraindicated interaction.
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Sintesi
Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
Cosa significa questa interazione in parole semplici
Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Glucocorticoid immunosuppression permits uncontrolled replication of live vaccinia virus.
Cosa fare
Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Dexamethasone
- Bcg vaccine live + Dexamethasone Controindicata
- Dexamethasone + Mifepristone Controindicata
- Dexamethasone + Rilpivirine Controindicata
- Dexamethasone + Varicella virus vaccine live Controindicata
- Dexamethasone + Yellow fever vaccine Controindicata
- Dexamethasone + Zoster vaccine live Controindicata
Domande frequenti
Can I take Dexamethasone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
How serious is the interaction between Dexamethasone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
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