Interazioni tra farmaci
Dexamethasone + Yellow fever vaccine
Gravità: Controindicata
Dexamethasone and Yellow fever vaccine: contraindicated interaction.
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Sintesi
Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
Cosa significa questa interazione in parole semplici
Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Glucocorticoid-induced immunosuppression impairs control of attenuated virus replication and blunts the immune response.
Cosa fare
Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Dexamethasone
- Bcg vaccine live + Dexamethasone Controindicata
- Dexamethasone + Mifepristone Controindicata
- Dexamethasone + Rilpivirine Controindicata
- Dexamethasone + Smallpox vaccine live Controindicata
- Dexamethasone + Varicella virus vaccine live Controindicata
- Dexamethasone + Zoster vaccine live Controindicata
Domande frequenti
Can I take Dexamethasone with Yellow fever vaccine?
MediHelp rates the interaction as contraindicated. Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
How serious is the interaction between Dexamethasone and Yellow fever vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
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