Interazioni tra farmaci
Dihydroergotamine intranasal + Frovatriptan
Gravità: Controindicata
Dihydroergotamine intranasal and Frovatriptan: contraindicated interaction.
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Sintesi
Both drugs are vasoconstrictors acting on serotonin receptors, and together they can cause prolonged vasospasm. Cases of peripheral and cerebral ischemia are described with triptan-ergot combinations.
Cosa significa questa interazione in parole semplici
Dihydroergotamine intranasal and Frovatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive vasoconstriction through 5-HT1B/1D agonism and ergot-mediated vascular receptor effects.
Cosa fare
Do not use within 24 hours of each other. Choose one agent for each migraine attack.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Frovatriptan
- Almotriptan + Frovatriptan Controindicata
- Dihydroergotamine + Frovatriptan Controindicata
- Eletriptan + Frovatriptan Controindicata
- Ergoloid mesylates + Frovatriptan Controindicata
- Ergotamine + Frovatriptan Controindicata
- Frovatriptan + Methylergonovine Controindicata
Domande frequenti
Can I take Dihydroergotamine intranasal with Frovatriptan?
MediHelp rates the interaction as contraindicated. Dihydroergotamine intranasal and Frovatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs are vasoconstrictors acting on serotonin receptors, and together they can cause prolonged vasospasm. Cases of peripheral and cerebral ischemia are described with triptan-ergot combinations.
How serious is the interaction between Dihydroergotamine intranasal and Frovatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use within 24 hours of each other. Choose one agent for each migraine attack.
What other medicines interact with Frovatriptan?
MediHelp also lists interactions of Frovatriptan with, for example, Almotriptan, Dihydroergotamine, Eletriptan. The full list is on the Frovatriptan page.
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