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Interazioni tra farmaci

Ergoloid mesylates + Frovatriptan

Gravità: Controindicata

Ergoloid mesylates and Frovatriptan: contraindicated interaction.

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Sintesi

Ergoloid mesylates are ergot derivatives, and combining them with a triptan may add to vasoconstriction. The risk of vasospastic ischemia is of concern, although ergoloids have weaker vasoconstrictor action than other ergots.

Cosa significa questa interazione in parole semplici

Ergoloid mesylates and Frovatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: Low

Perché avviene

Additive vasoconstrictive effects of a 5-HT1B/1D agonist and an ergot alkaloid.

Cosa fare

Avoid use within 24 hours of each other. Review whether ergoloid therapy is still necessary.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Ergoloid mesylates with Frovatriptan?

MediHelp rates the interaction as contraindicated. Ergoloid mesylates and Frovatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergoloid mesylates are ergot derivatives, and combining them with a triptan may add to vasoconstriction. The risk of vasospastic ischemia is of concern, although ergoloids have weaker vasoconstrictor action than other ergots.

How serious is the interaction between Ergoloid mesylates and Frovatriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid use within 24 hours of each other. Review whether ergoloid therapy is still necessary.

What other medicines interact with Frovatriptan?

MediHelp also lists interactions of Frovatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Frovatriptan page.

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