Interazioni tra farmaci
Frovatriptan + Methylergonovine
Gravità: Controindicata
Frovatriptan and Methylergonovine: contraindicated interaction.
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Sintesi
Methylergonovine is an ergot alkaloid with strong vasoconstrictor activity, and combining it with a triptan can cause prolonged vasospasm. This can lead to ischemia and hypertension.
Cosa significa questa interazione in parole semplici
Frovatriptan and Methylergonovine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive vasoconstriction from ergot alkaloid and 5-HT1B/1D agonist effects.
Cosa fare
Do not use within 24 hours of each other. Use alternative uterotonic or migraine therapy.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Frovatriptan
- Almotriptan + Frovatriptan Controindicata
- Dihydroergotamine intranasal + Frovatriptan Controindicata
- Dihydroergotamine + Frovatriptan Controindicata
- Eletriptan + Frovatriptan Controindicata
- Ergoloid mesylates + Frovatriptan Controindicata
- Ergotamine + Frovatriptan Controindicata
Domande frequenti
Can I take Frovatriptan with Methylergonovine?
MediHelp rates the interaction as contraindicated. Frovatriptan and Methylergonovine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylergonovine is an ergot alkaloid with strong vasoconstrictor activity, and combining it with a triptan can cause prolonged vasospasm. This can lead to ischemia and hypertension.
How serious is the interaction between Frovatriptan and Methylergonovine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use within 24 hours of each other. Use alternative uterotonic or migraine therapy.
What other medicines interact with Frovatriptan?
MediHelp also lists interactions of Frovatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Frovatriptan page.
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