Interazioni tra farmaci
Dihydroergotamine intranasal + Rizatriptan
Gravità: Controindicata
Dihydroergotamine intranasal and Rizatriptan: contraindicated interaction.
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Sintesi
Systemically absorbed intranasal dihydroergotamine adds vasoconstrictor effect to rizatriptan, risking prolonged vasospasm and ischemic events.
Cosa significa questa interazione in parole semplici
Dihydroergotamine intranasal and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive vasoconstriction via 5-HT1B/1D agonism and ergot vascular receptor effects.
Cosa fare
Do not combine; separate by at least 24 hours. Choose one therapy for each attack.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Rizatriptan
- Almotriptan + Rizatriptan Controindicata
- Dihydroergotamine + Rizatriptan Controindicata
- Eletriptan + Rizatriptan Controindicata
- Ergoloid mesylates + Rizatriptan Controindicata
- Ergotamine + Rizatriptan Controindicata
- Frovatriptan + Rizatriptan Controindicata
Domande frequenti
Can I take Dihydroergotamine intranasal with Rizatriptan?
MediHelp rates the interaction as contraindicated. Dihydroergotamine intranasal and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Systemically absorbed intranasal dihydroergotamine adds vasoconstrictor effect to rizatriptan, risking prolonged vasospasm and ischemic events.
How serious is the interaction between Dihydroergotamine intranasal and Rizatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; separate by at least 24 hours. Choose one therapy for each attack.
What other medicines interact with Rizatriptan?
MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine, Eletriptan. The full list is on the Rizatriptan page.
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