Interazioni tra farmaci
Dihydroergotamine + Rizatriptan
Gravità: Controindicata
Dihydroergotamine and Rizatriptan: contraindicated interaction.
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Sintesi
Rizatriptan and dihydroergotamine are both vasoconstrictors, and combined use may cause prolonged vasospasm. Risks include myocardial, cerebral and peripheral ischemia.
Cosa significa questa interazione in parole semplici
Dihydroergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Rizatriptan belongs to Central Nervous System.
Perché avviene
Additive vasoconstriction via 5-HT1B/1D agonism and ergot vascular receptor effects.
Cosa fare
Avoid concurrent use and leave at least 24 hours between doses. Use only one agent per attack.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Rizatriptan
- Almotriptan + Rizatriptan Controindicata
- Dihydroergotamine intranasal + Rizatriptan Controindicata
- Eletriptan + Rizatriptan Controindicata
- Ergoloid mesylates + Rizatriptan Controindicata
- Ergotamine + Rizatriptan Controindicata
- Frovatriptan + Rizatriptan Controindicata
Altre interazioni di Dihydroergotamine
- Almotriptan + Dihydroergotamine Controindicata
- Clarithromycin + Dihydroergotamine Controindicata
- Dihydroergotamine + Dopamine Controindicata
- Dihydroergotamine + Dronedarone Controindicata
- Dihydroergotamine + Efavirenz Controindicata
- Dihydroergotamine + Eletriptan Controindicata
Domande frequenti
Can I take Dihydroergotamine with Rizatriptan?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rizatriptan and dihydroergotamine are both vasoconstrictors, and combined use may cause prolonged vasospasm. Risks include myocardial, cerebral and peripheral ischemia.
How serious is the interaction between Dihydroergotamine and Rizatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and leave at least 24 hours between doses. Use only one agent per attack.
What other medicines interact with Rizatriptan?
MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Eletriptan. The full list is on the Rizatriptan page.
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