Interazioni tra farmaci
Elvitegravir / cobicistat / emtricitabine / tenofovir df + Raltegravir
Gravità: Controindicata
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.
Cosa significa questa interazione in parole semplici
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Therapeutic duplication of two integrase strand transfer inhibitors; no established pharmacokinetic mechanism.
Cosa fare
Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Raltegravir
Domande frequenti
Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Raltegravir?
MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.
How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.
What other medicines interact with Raltegravir?
MediHelp also lists interactions of Raltegravir with, for example, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate, Aluminum hydroxide. The full list is on the Raltegravir page.
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