Interazioni tra farmaci
Everolimus + Influenza virus vaccine quadrivalent intranasal
Gravità: Controindicata
Everolimus and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
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Sintesi
The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by everolimus. Vaccine response may also be reduced. Live vaccines are generally avoided in patients on everolimus.
Cosa significa questa interazione in parole semplici
Everolimus and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Everolimus-induced immunosuppression impairs control of live attenuated virus replication and reduces vaccine response.
Cosa fare
Do not give the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Everolimus
- Bcg vaccine live + Everolimus Controindicata
- Everolimus + Levoketoconazole Controindicata
- Everolimus + Measles mumps and rubella vaccine live Controindicata
- Everolimus + Measles mumps rubella and varicella vaccine live Controindicata
- Everolimus + Measles vaccine Controindicata
- Everolimus + Ritonavir Controindicata
Domande frequenti
Can I take Everolimus with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Everolimus and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by everolimus. Vaccine response may also be reduced. Live vaccines are generally avoided in patients on everolimus.
How serious is the interaction between Everolimus and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Levoketoconazole, Measles mumps and rubella vaccine live. The full list is on the Everolimus page.
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