Interazioni tra farmaci
Everolimus + Measles mumps and rubella vaccine live
Gravità: Controindicata
Everolimus and Measles mumps and rubella vaccine live: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
This live attenuated vaccine can cause disseminated vaccine-strain infection in patients immunosuppressed by everolimus, and the immune response may also be reduced.
Cosa significa questa interazione in parole semplici
Everolimus and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Immunosuppression from mTOR inhibition impairs control of live attenuated virus replication and reduces vaccine response.
Cosa fare
Do not administer during everolimus therapy. Give at least several weeks before starting everolimus where feasible, and check immunity serologically if exposure occurs.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Everolimus
- Bcg vaccine live + Everolimus Controindicata
- Everolimus + Influenza virus vaccine quadrivalent intranasal Controindicata
- Everolimus + Levoketoconazole Controindicata
- Everolimus + Measles mumps rubella and varicella vaccine live Controindicata
- Everolimus + Measles vaccine Controindicata
- Everolimus + Ritonavir Controindicata
Domande frequenti
Can I take Everolimus with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Everolimus and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated vaccine can cause disseminated vaccine-strain infection in patients immunosuppressed by everolimus, and the immune response may also be reduced.
How serious is the interaction between Everolimus and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during everolimus therapy. Give at least several weeks before starting everolimus where feasible, and check immunity serologically if exposure occurs.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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