Interazioni tra farmaci
Fluorouracil + Temoporfin
Gravità: Moderata
Fluorouracil and Temoporfin: moderate interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Temoporfin causes prolonged skin photosensitivity, and topical fluorouracil can also increase photosensitivity. Together they may worsen phototoxic skin reactions.
Cosa significa questa interazione in parole semplici
Fluorouracil and Temoporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluorouracil belongs to Oncology; Temoporfin belongs to Oncology.
Perché avviene
Additive photosensitising effects on the skin.
Cosa fare
Avoid topical fluorouracil on exposed skin around the time of temoporfin photosensitivity, and keep strict light protection. Review skin for phototoxic reactions.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Fluorouracil
- Adenovirus types 4 and 7 live + Fluorouracil Maggiore
- Axicabtagene ciloleucel + Fluorouracil Maggiore
- Belatacept + Fluorouracil Maggiore
- Brexucabtagene autoleucel + Fluorouracil Maggiore
- Ciltacabtagene autoleucel + Fluorouracil Maggiore
- Deferiprone + Fluorouracil Maggiore
Domande frequenti
Can I take Fluorouracil with Temoporfin?
MediHelp rates the interaction as moderate. Fluorouracil and Temoporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Temoporfin causes prolonged skin photosensitivity, and topical fluorouracil can also increase photosensitivity. Together they may worsen phototoxic skin reactions.
How serious is the interaction between Fluorouracil and Temoporfin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid topical fluorouracil on exposed skin around the time of temoporfin photosensitivity, and keep strict light protection. Review skin for phototoxic reactions.
What other medicines interact with Fluorouracil?
MediHelp also lists interactions of Fluorouracil with, for example, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel, Belatacept. The full list is on the Fluorouracil page.
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