Interazioni tra farmaci
Influenza virus vaccine quadrivalent intranasal + Mercaptopurine
Gravità: Controindicata
Influenza virus vaccine quadrivalent intranasal and Mercaptopurine: contraindicated interaction.
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Sintesi
The intranasal vaccine contains live attenuated virus, which may replicate more in immunosuppressed patients. Mercaptopurine also may reduce the immune response.
Cosa significa questa interazione in parole semplici
Influenza virus vaccine quadrivalent intranasal and Mercaptopurine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Immunosuppression impairs control of live attenuated virus replication.
Cosa fare
Avoid the live intranasal vaccine in patients on mercaptopurine and use an inactivated injectable influenza vaccine instead.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Mercaptopurine
- Adenovirus types 4 and 7 live + Mercaptopurine Controindicata
- Azathioprine + Mercaptopurine Controindicata
- Bcg vaccine live + Mercaptopurine Controindicata
- Febuxostat + Mercaptopurine Controindicata
- Mercaptopurine + Smallpox vaccine live Controindicata
- Adalimumab + Mercaptopurine Maggiore
Domande frequenti
Can I take Influenza virus vaccine quadrivalent intranasal with Mercaptopurine?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Mercaptopurine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal vaccine contains live attenuated virus, which may replicate more in immunosuppressed patients. Mercaptopurine also may reduce the immune response.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Mercaptopurine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine in patients on mercaptopurine and use an inactivated injectable influenza vaccine instead.
What other medicines interact with Mercaptopurine?
MediHelp also lists interactions of Mercaptopurine with, for example, Adenovirus types 4 and 7 live, Azathioprine, Bcg vaccine live. The full list is on the Mercaptopurine page.
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