Interazioni tra farmaci
Magnesium hydroxide + Sodium polystyrene sulfonate
Gravità: Moderata
Magnesium hydroxide and Sodium polystyrene sulfonate: moderate interaction.
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Sintesi
Magnesium hydroxide taken with sodium polystyrene sulfonate can lead to metabolic alkalosis because the resin binds the magnesium, leaving bicarbonate unneutralized. Rarely, intestinal obstruction from non-absorbable antacid and resin has been described.
Cosa significa questa interazione in parole semplici
Magnesium hydroxide and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium hydroxide belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.
Perché avviene
The resin binds magnesium in the gut, preventing neutralization of bicarbonate and leading to systemic alkalosis.
Cosa fare
Avoid giving magnesium-containing antacids or laxatives with the resin, and separate doses by at least 2 hours if both are needed. Monitor acid-base status and electrolytes.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Magnesium hydroxide
- Ciprofloxacin + Magnesium hydroxide Maggiore
- Dolutegravir + Magnesium hydroxide Maggiore
- Gemifloxacin + Magnesium hydroxide Maggiore
- Levofloxacin + Magnesium hydroxide Maggiore
- Magnesium hydroxide + Moxifloxacin Maggiore
- Magnesium hydroxide + Ofloxacin Maggiore
Altre interazioni di Sodium polystyrene sulfonate
- Meloxicam + Sodium polystyrene sulfonate Maggiore
- Sodium polystyrene sulfonate + Sorbitol Maggiore
- Calcium carbonate + Sodium polystyrene sulfonate Moderata
- Deflazacort + Sodium polystyrene sulfonate Moderata
- Levothyroxine + Sodium polystyrene sulfonate Moderata
- Lithium + Sodium polystyrene sulfonate Moderata
Domande frequenti
Can I take Magnesium hydroxide with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Magnesium hydroxide and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium hydroxide taken with sodium polystyrene sulfonate can lead to metabolic alkalosis because the resin binds the magnesium, leaving bicarbonate unneutralized. Rarely, intestinal obstruction from non-absorbable antacid and resin has been described.
How serious is the interaction between Magnesium hydroxide and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving magnesium-containing antacids or laxatives with the resin, and separate doses by at least 2 hours if both are needed. Monitor acid-base status and electrolytes.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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