Interazioni tra farmaci
Oxymorphone + Selegiline transdermal
Gravità: Controindicata
Oxymorphone and Selegiline transdermal: contraindicated interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
MAO inhibitors have been associated with serious reactions with opioids, including serotonin syndrome, hypotension, hyperpyrexia and CNS depression. Oxymorphone labeling advises against use with MAOIs.
Cosa significa questa interazione in parole semplici
Oxymorphone and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
MAO inhibition may potentiate opioid effects and serotonergic or adrenergic toxicity; mechanism with oxymorphone is not fully defined.
Cosa fare
Avoid concurrent use and for at least 14 days after stopping the MAOI. Choose an alternative analgesic.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Oxymorphone e Selegiline transdermal, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Oxymorphone
- Alvimopan + Oxymorphone Controindicata
- Ethanol + Oxymorphone Controindicata
- Isocarboxazid + Oxymorphone Controindicata
- Olanzapine / samidorphan + Oxymorphone Controindicata
- Oxymorphone + Phenelzine Controindicata
- Oxymorphone + Sodium oxybate Controindicata
Domande frequenti
Can I take Oxymorphone with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Oxymorphone and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAO inhibitors have been associated with serious reactions with opioids, including serotonin syndrome, hypotension, hyperpyrexia and CNS depression. Oxymorphone labeling advises against use with MAOIs.
How serious is the interaction between Oxymorphone and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and for at least 14 days after stopping the MAOI. Choose an alternative analgesic.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
