医薬品リファレンス

Aztreonam

Aztreonam is a medicine in the class anti bacterial. It is used for cystic fibrosis.

薬効分類: Anti Bacterial
効能・効果: cystic fibrosis

最終更新日 13 10月 2026

医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。

このページの臨床コンテンツは英語でのみ提供されています。

要点

薬効分類: Anti Bacterial
ATCコード: J01DF01
一般的な剤形: 注射剤
一般的な規格: 1 g, 500 mg
既知の相互作用: 16 (中等度: 5 · 軽度: 11)
商品名: 5
国・市場: 3

剤形、規格、商品名は国によって異なります。お手元の製品をご確認ください。

何に使われるか

作用のしくみ

Monobactam; inhibits cell wall synthesis by binding to penicillin binding proteins

成人の通常用量（添付文書の要約）

Systemic Infections (Moderately severe): 1-2 g IV/IM q8-12hr; not to exceed 8 g/day

添付文書の最初の用法・用量の行のみの要約です。用法・用量の全項目はアプリでご覧いただけます。

妊娠と授乳

妊娠: Safe Crosses the placenta; animal studies showed no harm and limited human use has not shown problems. As a beta-lactam it is an acceptable option when a serious gram-negative infection needs treatment.
授乳: Safe Milk levels are under 1% of maternal blood levels and it is poorly absorbed from the infant gut. US label suggests considering a temporary pause; LactMed: acceptable. Watch for diarrhoea or thrush. Inhaled aztreonam gives even lower exposure.

報告されている副作用

Cough
Fever
Nasal congestion
Sore throat
Wheezing

注意が必要な方

May cause bronchospasm, stop treatment if chest tightness develops during nebulizer use
In patients with impaired hepatic or renal function, appropriate monitoring is recommended during therapy
If aminoglycoside is used concurrently, especially if high dosages of former are used or if therapy is prolonged, renal function should be monitored

妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。

主な相互作用 (16)

Aztreonam + Cefoxitin Moderate
Aztreonam + Cholera vaccine Moderate
Aztreonam + Microbiota Moderate
Aztreonam + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderate
Aztreonam + Typhoid vaccine live Moderate
Amikacin + Aztreonam Minor
Amoxicillin + Aztreonam Minor
Amoxicillin-clavulanic acid + Aztreonam Minor
Aztreonam + Bcg vaccine live Minor
Aztreonam + Cefpirome Minor

All 16 interactions, with severity and what to do

Pro+会員向け

ページ全体を見る

アカウントを作成してPro+トライアルを始めると、Aztreonamの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。

Dosing by age, kidney and liver function, and further dose lines
Renal and hepatic dose adjustments
Paediatric dosing
Pharmacokinetics
Patient counselling points
Food interactions
IV preparation and dilution

無料アカウントを作成ログイン

WebでPro+を14日間無料でお試し。カード登録不要。

よくある質問

What is Aztreonam used for?

Aztreonam is a medicine in the class anti bacterial. It is used for Cystic fibrosis, Pseudomonal infections, Sepsis, Urinary tract infections.

What side effects have been reported with Aztreonam?

Cough, Fever, Nasal congestion, Sore throat, Wheezing.

Can Aztreonam be taken in pregnancy or while breastfeeding?

Pregnancy: Safe. Crosses the placenta; animal studies showed no harm and limited human use has not shown problems. As a beta-lactam it is an acceptable option when a serious gram-negative infection needs treatment. Breastfeeding: Safe. Milk levels are under 1% of maternal blood levels and it is poorly absorbed from the infant gut. US label suggests considering a temporary pause; LactMed: acceptable. Watch for diarrhoea or thrush. Inhaled aztreonam gives even lower exposure.

What does Aztreonam interact with?

MediHelp lists 16 known interactions for Aztreonam. Moderate: 5 · Minor: 11. The most serious include Cefoxitin, Cholera vaccine, Microbiota.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

ダウンロード：App Store 入手：Google Play

A–Zで探す · 医薬品リファレンス