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相互作用

Amikacin + Aztreonam

重症度: 軽度

Amikacin and Aztreonam: minor interaction.

最終更新日

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概要

Aztreonam and amikacin are often combined deliberately for additive or synergistic activity against Pseudomonas and Enterobacterales. The pairing is generally beneficial, though aminoglycoside nephrotoxicity and ototoxicity still apply.

この相互作用をわかりやすく説明すると

Amikacin and Aztreonam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amikacin belongs to Anti Bacterial; Aztreonam belongs to Anti Bacterial.

エビデンスレベル: Moderate

なぜ起こるのか

Complementary antibacterial mechanisms: cell wall synthesis inhibition may enhance aminoglycoside uptake.

対処法

Use as clinically indicated; monitor serum creatinine and amikacin levels, and adjust the amikacin dose for renal function.

薬剤師に尋ねること

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+会員向け

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アカウントを作成してPro+トライアルを始めると、AmikacinとAztreonamの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Amikacin with Aztreonam?

MediHelp rates the interaction as minor. Amikacin and Aztreonam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aztreonam and amikacin are often combined deliberately for additive or synergistic activity against Pseudomonas and Enterobacterales. The pairing is generally beneficial, though aminoglycoside nephrotoxicity and ototoxicity still apply.

How serious is the interaction between Amikacin and Aztreonam?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use as clinically indicated; monitor serum creatinine and amikacin levels, and adjust the amikacin dose for renal function.

What other medicines interact with Aztreonam?

MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Microbiota. The full list is on the Aztreonam page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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